I was answering in a public forum about creatine. Hope it explains the science in simple terms for all...
Here is the science behind creatine...
To generate energy by muslce fibers ATP(adenosine triphosphate) is broken down to ADP(adenosine diphosphate).ATP is the main contributor for musle contraction and in the process Phorporous is released and ADP is formed.
To maintain energy levels , the released phorporous has to combine back with ADP to become ATP. so that continuous flow of energy can be formed.
If you see ADP -> ATP and ATP-> ADP are opposing process and our body as always is extremely adaptable and inteligent. so it senses energy production for the moment is important and utilizes ATP and does not provide enough importance to re attach bring phorporous from blood stream into the muscle so that ATP balanec is maintained.
the solution to this problem is creatine which can readily bring in creatine phosphate for the reaction of (ADP + CP -> ATP ). So ATP balance is restored and muscle contractions and energy levels can persist longer..
i removed out a lot of scientific BS that will be tough to understand and brough it in simple terms... Scientists please excuse lols....
AS per PUBMED - there is nothing called as creatine receptors... so on paper you can use it as long as you want.
Your body can not utilize all creatine you consume so there will be wastage. ineveitable.
Practical experience - staying on high carb or high protein always also sucks as your body adapts to it.. Not receptor shit but adaptation shit.
So upping dose or discontinuing for some time can actually help.
Hope the content is straight forward and to the point
